Lymes Disease
Lyme disease, Lyme
borreliosis is an emerging infectious disease caused by at least
three species of bacteria belonging to the genus Borrelia Borrelia burgdorferi sensu stricto is
the main cause of Lyme disease in North America, whereas Borrelia
afzelii and Borrelia
garinii cause most European cases. The disease
is named after the towns of Lyme and Old
Lyme, Connecticut, USA, where a number of cases were identified in 1975.
Although Allen Steere realized that Lyme disease was a tick-borne
disease in 1978, the cause of the disease remained a mystery until 1981,
when B. burgdorferi was
identified by Willy Burgdorfer.
Lyme disease is the
most common tick-borne disease in the Northern Hemisphere. Borrelia is transmitted to
humans by the bite of infected ticks belonging to a few species of the genus Ixodes ("hard ticks"). Early
symptoms may include fever, headache, fatigue, depression,
and a characteristic circular skin rash called erythema migrans (EM).
Left untreated, later symptoms may involve the joints, heart, and central
nervous system. In most cases, the infection and its symptoms are eliminated by antibiotics,
especially if the illness is treated early. Delayed or inadequate treatment
can lead to the more serious symptoms, which can be disabling and difficult to
treat.
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